Sanford married Frances Nancy Holland about 1856. Frances (daughter of Richard Holland and Louisa Etta Bates) was born on 12 Mar 1838 in Cherokee County, Georgia; died on 15 Aug 1905 in Tyler, Smith County, Texas. [Group Sheet] [Family Chart]

1. James Washington Epperson was born on 25 Dec 1857 in Cherokee County, Georgia; died on 15 Apr 1935 in Minden, Webster County, La..
2. William Franklin Epperson was born on 20 Oct 1859 in Cherokee County, Georgia; died on 31 May 1860.
3. Private
4. Private
5. George Spencer Epperson was born on 08 May 1866; died on 26 Mar 1936 in Tyler, Smith County, Texas..
6. Julie Emily Josephine Epperson was born on 08 Jul 1868; died before 1905.
7. Mary Anna Bessie Epperson was born on 14 Jul 1870 in Meriwether County, Georgia; died on 18 Apr 1920 in Austin, Travis County, Texas..
8. Martha Emma Rossa Epperson was born on 02 Nov 1872; died before 1905.
9. John Ira Epperson was born on 28 May 1875; died after 1941 in Texas.
10. Private